KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERCC6
All Species:
8.48
Human Site:
T1111
Identified Species:
15.56
UniProt:
Q03468
Number Species:
12
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q03468
NP_000115.1
1493
168416
T1111
N
D
R
L
G
E
E
T
N
A
V
S
G
P
E
Chimpanzee
Pan troglodytes
XP_507781
1491
168031
T1109
N
D
R
L
G
E
E
T
N
A
V
S
G
P
E
Rhesus Macaque
Macaca mulatta
XP_001107536
1496
168876
T1114
N
D
R
L
G
G
E
T
N
A
V
S
G
L
E
Dog
Lupus familis
XP_534944
1486
168108
E1104
T
G
S
G
G
P
E
E
K
T
K
A
V
P
I
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
NP_001100766
1325
148468
V964
P
L
V
S
D
T
S
V
N
G
A
T
V
M
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508174
968
109820
E607
L
T
A
G
T
I
E
E
K
I
Y
H
R
Q
I
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24368
1027
118855
Q666
A
G
T
S
S
V
Y
Q
F
E
G
E
D
W
R
Honey Bee
Apis mellifera
XP_001120586
932
107557
W571
A
Q
A
R
E
R
A
W
R
I
G
Q
N
K
N
Nematode Worm
Caenorhab. elegans
P41877
1009
116656
E648
E
K
M
G
K
I
D
E
N
N
L
R
N
M
T
Sea Urchin
Strong. purpuratus
XP_001193315
953
107227
R592
D
G
V
A
A
A
S
R
V
G
H
V
H
S
A
Poplar Tree
Populus trichocarpa
XP_002307656
1206
134941
A844
N
P
S
T
D
M
Q
A
R
E
R
A
W
R
I
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RWY3
1057
122611
D696
E
E
A
T
A
E
L
D
A
K
M
K
K
F
T
Baker's Yeast
Sacchar. cerevisiae
P40352
1085
124509
D724
R
F
N
N
E
S
F
D
V
F
L
L
T
T
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.2
83.3
N.A.
N.A.
70.1
N.A.
44.6
N.A.
N.A.
N.A.
N.A.
20
31.4
20.6
36.4
Protein Similarity:
100
99.4
97.9
89.1
N.A.
N.A.
76.4
N.A.
52.2
N.A.
N.A.
N.A.
N.A.
35.7
43.8
35.7
45.8
P-Site Identity:
100
100
86.6
20
N.A.
N.A.
13.3
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
0
0
6.6
0
P-Site Similarity:
100
100
86.6
26.6
N.A.
N.A.
20
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
0
0
20
6.6
Percent
Protein Identity:
29.4
N.A.
N.A.
23.5
28.4
N.A.
Protein Similarity:
44.9
N.A.
N.A.
38.2
43.9
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
20
N.A.
N.A.
20
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
24
8
16
8
8
8
8
24
8
16
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
24
0
0
16
0
8
16
0
0
0
0
8
0
0
% D
% Glu:
16
8
0
0
16
24
39
24
0
16
0
8
0
0
31
% E
% Phe:
0
8
0
0
0
0
8
0
8
8
0
0
0
8
0
% F
% Gly:
0
24
0
24
31
8
0
0
0
16
16
0
24
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
8
8
0
0
% H
% Ile:
0
0
0
0
0
16
0
0
0
16
0
0
0
0
24
% I
% Lys:
0
8
0
0
8
0
0
0
16
8
8
8
8
8
0
% K
% Leu:
8
8
0
24
0
0
8
0
0
0
16
8
0
8
0
% L
% Met:
0
0
8
0
0
8
0
0
0
0
8
0
0
16
0
% M
% Asn:
31
0
8
8
0
0
0
0
39
8
0
0
16
0
8
% N
% Pro:
8
8
0
0
0
8
0
0
0
0
0
0
0
24
0
% P
% Gln:
0
8
0
0
0
0
8
8
0
0
0
8
0
8
0
% Q
% Arg:
8
0
24
8
0
8
0
8
16
0
8
8
8
8
16
% R
% Ser:
0
0
16
16
8
8
16
0
0
0
0
24
0
8
0
% S
% Thr:
8
8
8
16
8
8
0
24
0
8
0
8
8
8
16
% T
% Val:
0
0
16
0
0
8
0
8
16
0
24
8
16
0
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
8
8
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _